Carrier and Reproductive Risk
Secure Match
Checks both partners for recessive conditions they could pass on.
Expanded carrier screening across hundreds of recessive and X-linked conditions.
- Specimen
- EDTA blood or buccal swab (both partners)
- Methodology
- NGS carrier panel
- Category
- Carrier and Reproductive Risk
Pricing is available through your BioBloom portal or on request.
How it works
- 1
Order
Place the order through the BioBloom portal.
- 2
Sample
Collect the sample — EDTA blood or buccal swab (both partners).
- 3
Analysis
Laboratory analysis — NGS carrier panel.
- 4
Report
Secure report delivered to your clinic through the portal.
What’s in the report
Carrier status across the panel, with couple risk highlighted where both partners share a condition.
Research & evidence
Carrier screening established; adjuncts developingCarrier & reproductive risk
Expanded carrier screening is the ACMG-endorsed standard for identifying reproductive risk. Embryo polygenic scoring and immunogenetic adjuncts are active areas of research, best used within a specialist context.
Limitations: KIR-HLA-C is described by researchers in the field as too early for clinical intervention (Moffett 2016), and the ALIFE2 randomised trial found heparin did not improve live birth in inherited thrombophilia with recurrent loss. Embryo polygenic risk scoring has no established clinical utility and is not a routine test.
Read the research
