Evidence that the endometrial microbiota has an effect on implantation success or failure
Moreno et al.
Education & insights
A clinically grounded introduction to the microbial environment inside the uterus - what it is, how it relates to fertility, how testing works, and what to do with a result. Written to be readable by patients and useful to clinicians.

The series

The microbial environment inside the uterus. What it is, why it matters for fertility, and how BioBloom measures it.
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What the evidence shows about the endometrial microbiome, implantation, and pregnancy outcomes.
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How BioBloom measures the microbial environment inside the uterus, and what the test actually involves.
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Clinical next steps after an endometrial microbiome test. Treatment options, retesting, and how results fit into a fertility care plan.
ReadA note on reading this literature
The endometrium carries a fraction of the bacterial load found in the vagina or gut. At those biomass levels, contamination from reagents, swabs, the cervix, or the lab itself can swamp the real signal. Studies that don't account for this can produce misleading taxonomies.
When comparing studies, the questions worth asking are: was sampling transcervical or at hysterectomy, was a double-lumen catheter used, were negative controls sequenced, and was contamination partitioning applied?
BioBloom holds its own methodology to the same standards we apply when reading the literature.
A decade of research
16 papers · 2015-2025
The library
A curated set, not a comprehensive index. Each entry links to the primary source and expands inline for study design, sample, and limitations.
Curated · Last reviewed April 2026
Moreno et al.
Moreno et al.
Hiratsuka et al.
Kyono et al.
Endometrial microbiome testing is ordered through partner fertility clinics. Speak with your fertility specialist about whether the assay is appropriate for your workup.