Embryo Testing (PGT)

Secure Select (niPGT-A)

Chromosome screening from the embryo’s culture fluid — used alongside, not instead of, biopsy PGT-A.

Analyses embryonic cell-free DNA in spent culture medium as a biopsy-free adjunct to, not a replacement for, trophectoderm-biopsy PGT-A.

Specimen
Spent embryo culture medium
Methodology
NGS of embryonic cell-free DNA
Category
Embryo Testing (PGT)

Pricing is available through your BioBloom portal or on request.

This test requires genetic counselling and written consent — your clinic will confirm this at ordering.

How it works

  1. 1

    Order

    Place the order through the BioBloom portal.

  2. 2

    Sample

    Collect the sample — Spent embryo culture medium.

  3. 3

    Analysis

    Laboratory analysis — NGS of embryonic cell-free DNA.

  4. 4

    Report

    Secure report delivered to your clinic through the portal.

What’s in the report

Biopsy-free aneuploidy screen per embryo (investigational).

Research & evidence

PGT-M/SR established; PGT-A used selectively

PGT & embryo testing

PGT-M and PGT-SR are well-established for monogenic disease and structural rearrangements. PGT-A and non-invasive PGT-A are best used selectively, with the clearest signal in older patients per transfer.

Limitations: Randomised trials have not shown PGT-A to improve cumulative live birth in unselected patients: it selects between existing embryos rather than improving them. niPGT-A from spent culture medium is investigational, and its concordance with trophectoderm biopsy varies between laboratories.

Read the research

Accreditations & governance

  • ICO logo

    ICO registered

  • MHRA logo

    MHRA registered

  • ISO logo

    ISO 15189 accredited laboratory.

  • Cyber Essentials